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Year : 2021  |  Volume : 8  |  Issue : 2  |  Page : 64-67

Effect of Lagerstroemia Speciosa (L.) Pers. (Jarula) leaves powder as a hypoglycemic agent in the management of Type 2 diabetes mellitus: An interventional study

Department of Kayachikitsa, North Eastern Institute of Ayurveda and Homoeopathy, Ministry of AYUSH, Government of India, Shillong, Meghalaya, India

Correspondence Address:
Bishnu Choudhury
Department of Kayachikitsa, North Eastern Institute of Ayurveda and Homoeopathy, Ministry of AYUSH, Government of India, Mawdiangdiang, Shillong - 793 018, Meghalaya
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/AYUHOM.AYUHOM_4_22

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Background: Perusal of history revels the earliest description of Madhumeha (diabetes mellitus [DM]) is found in Vedic literature of India. The hypoglycemic effect of Lagerstroemia speciosa (L.) Pers. has been date back from the old writing of Ayurveda (Bhavaprakash Nighantu). Objective: The objective is to assess the efficacy of L. speciosa (L.) Pers as an oral hypoglycemic agent. Materials and Methods: The present study is a single group, open label, clinical trial with pre-post follow-up test design on 100 subjects of type 2 DM. Subjects were intervened with L. speciosa (L.) Pers. leaves powder in the dose of 12 g daily in two divided dose ½ h before breakfast and dinner with warm water for 90 days along with advice for standard control of diet and lifestyle modification. The result of the study was determined by the changes in fasting and postprandial blood sugar and glycosylated hemoglobin (HbA1C) level before and after completion of study. Statistical analysis was done using all values which are expressed as mean ± standard deviation and “Z” test. The results were assessed through “P” value. Results: After 90 days of intervention, mean laboratory measured fasting and postprandial blood glucose showed a decrease from 168 and 202 mg/dl to 135 and 166 mg/dl respectively. Reduction in mean HbA1C was also observed from 7.3% to 6.5%. The rate of shift of grade was observed statistically significant (P < 0.01) in all parameters. Conclusion: Leaf's powder of L. speciosa (L.) Pers. showed significant hypoglycemic effect.

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