A Placebo-controlled Clinical Evaluation of Gokshuradi Taila Matravasti in the Management of Gridhrasi vata (Sciatica)

Abhishek Bhattacharjee

doi:10.4103/AYUHOM.AYUHOM_11_21

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ORIGINAL ARTICLE

Year : 2020 \| Volume : 7 \| Issue : 1 \| Page : 20-26

A Placebo-controlled Clinical Evaluation of Gokshuradi Taila Matravasti in the Management of Gridhrasi vata (Sciatica) Abhishek Bhattacharjee Department of Panchakarma, College of Ayurveda, North Eastern Institute of Ayurveda and Homoeopathy, Shillong, Meghalaya, India Correspondence Address: Dr. Abhishek Bhattacharjee Department of Panchakarma, College of Ayurveda, North Eastern Institute of Ayurveda and Homoeopathy, Mawdiangdiang, Shillong, Meghalaya India Source of Support: None, Conflict of Interest: None DOI: 10.4103/AYUHOM.AYUHOM_11_21

Background: Gridhrasi is one of the Vataja Nanatmaja diseases which we commonly come across in our clinical practice. A radiating pain starting from the lower back up to the foot is the cardinal feature often associated with stiffness, pricking, and tingling sensation which are very similar to the symptoms of sciatica. Gokshuradi Taila Matravasti is indicated for Gridhrasi in Vangasena Samhita. Aim and Objective: Placebo-controlled clinical evaluation of Gokshuradi Taila Matravasti in the patients of Gridhrasi (sciatica). Materials and Methods: A single-blind, placebo-controlled clinical study was conducted with pretest and posttest design where 60 patients suffering from Gridhrasi (sciatica) were selected and randomly allocated into two groups (Group-A and Group-B) after initial screening. The patients of Group-A were treated with Gokshuradi Taila Matravasti and Group-B with rectal administration of specially designed placebo drug for 14 days. Patients were observed for a total follow-up period of 30 days with three stages of assessment on 0, 15^th, and 30^th day. The assessment of results was made by adopting the standard methods of international scoring including pain, neurological deficit, functional ability, functional disability, and also selective signs and symptoms. Statistically significant test for comparison was done by ANOVA followed by Tukey's multiple comparison test. Results: Statistically significant relief was observed in the patients of Group-A, treated with Gokshuradi Taila Matravasti compared to Group-B (control group) at the end of the study.



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