| REVIEW ARTICLE |
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| Year : 2019 | Volume
: 6
| Issue : 2 | Page : 60-64 |
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Safety Profile of Manahshila and its Formulations: An Evidence-Based Study
Sarika Makwana1, Rahul Kanjibhai Shingadiya2, Prashant Bedarkar1, Biswajyoti J Patgiri1
1 Department of Rasa Shashtra and Bhaishajya Kalpana, I.P.G.T. and R.A, Gujarat Ayurved University, Jamnagar, Gujarat, India
2 Departmet of Rasashashtra and Bhaishajya Kalpana, Government Ayurveda College, Junagadh, Gujarat, India
Correspondence Address:
Dr. Sarika Makwana
Department of Rasa Shashtra and Bhaishajya Kalpana, I.P.G.T. and R.A, Gujarat Ayurved University, Jamnagar - 361 008, Gujarat
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/AYUHOM.AYUHOM_10_21
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Manahshila (Realgar, As2S3) is a widely utilized drug in Ayurvedic therapeutics since the Samhita period. It is one of the mineral drugs, on few researches have been conducted which cover the area of quality control and safety profile. Therefore, the present work was conducted to review published researches of Manahshila and its containing formulations which related to pharmaceutico–analytical studies and safety concern. Published articles on toxicity studies and pharmacological studies of Manahshila and its formulations were reviewed through various search engines and databases such as Google, Google Scholar, Yahoo, Springer, Omics, Medknow, PubMed, and J gate. Results: A total of 12 published research articles were summarized. Among them, three were on pharmaceutico–analytical study; four on pharmacological study and toxicity study of Manahshila; three on pharmaceutico–analytical study; and two on pharmacological study and toxicity study of Manahshila and formulations containing Manahshila. Above mentioned published researches on Manahshila evidently conclude that Manahshila and its formulations are safe to be used in human to treat different diseases conditions.
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